4-三甲基硅烷氧基环己基-3-烯-甲醛合成路线 （共 8 条）
反应条件
1: LiAlH4 / diethyl ether / 1.) from -78 deg C to RT, 2 h, 2.) RT, 30 min 2: 15percent aq. NaOH / methanol / 0.5 h / Ambient temperature View Scheme
参考文献
Radchenko, Dmytro S.; Kopylova, Nataliya; Grygorenko, Oleksandr O.; Komarov, Igor V.
Journal of Organic Chemistry, 2009 , vol. 74, # 15 p. 5541 - 5544
反应条件
methanol 24 h; Ambient temperature;
参考文献
Makin, S. M.; Shavrygina, O. A.; Nguyen, Fong Tung
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 11 p. 2082 - 2087
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 11 p. 2309 - 2315
反应条件
1: LiAlH4 / diethyl ether / 1.) from -78 deg C to RT, 2 h, 2.) RT, 30 min 2: 15percent aq. NaOH / methanol / 0.5 h / Ambient temperature 3: 92.6 percent / pyridine / 48 h / 0 °C View Scheme
参考文献
Yin, Tyze-Kuan; Lee, Jon Gun; Borden, Weston Thatcher
Journal of Organic Chemistry, 1985 , vol. 50, # 4 p. 531 - 534
反应条件
1: 75 percent / DBU / tetrahydrofuran / 8 h 2: 100 percent / H2 / Pd/C / ethyl acetate / 6 h View Scheme
参考文献
Taylor, Edward C.; Dowling, James E.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 4 p. 453 - 456
反应条件
hydroquinone in toluene
24 h; Heating;
参考文献
Rigby, James H.; Kotnis, Atul; Kramer, James
Journal of Organic Chemistry, 1990 , vol. 55, # 17 p. 5078 - 5088
反应条件
1: LiAlH4 / diethyl ether / 1.) from -78 deg C to RT, 2 h, 2.) RT, 30 min
2: 15percent aq. NaOH / methanol / 0.5 h / Ambient temperature
3: 92.6 percent / pyridine / 48 h / 0 °C
4: KH / tetrahydrofuran / 50 °C
View Scheme
参考文献
Yin, Tyze-Kuan; Lee, Jon Gun; Borden, Weston Thatcher
Journal of Organic Chemistry, 1985 , vol. 50, # 4 p. 531 - 534
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
Hydrolysis; Wittig olefination; 8 h;
参考文献
Taylor, Edward C.; Dowling, James E.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 4 p. 453 - 456
反应条件
ammonium chloride
2.5 h; Heating;
参考文献
Gangjee; Zaveri; Kothare; Queener
Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3660 - 3668
