4-苄基 1-叔丁基 L-天冬氨酸酯合成路线 （共 8 条）
反应条件
perchloric acid in water T=20°C; 18 h;
参考文献
WO2006/2873 A2, ;
Page/Page column 39-40 ;
反应条件
sulfuric acid in 1,4-dioxane 20 h; Ambient temperature;
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 105, # 1-4 p. 129 - 144
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 6 h; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 7, # 6 p. 1064 - 1067
反应条件
1: 67 percent / benzene / 3 h / Heating 2: 1.) CuSO4, 5 M NaOH, 2.) EDTA / 1.) EtOH, 32 deg C, 1 h, 2.) H2O, 100 deg C, 10 min 3: 53 percent / conc. H2SO4 / 20 h / -25 - 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 2 p. 391 - 401
反应条件
1: 1.) CuSO4, 5 M NaOH, 2.) EDTA / 1.) EtOH, 32 deg C, 1 h, 2.) H2O, 100 deg C, 10 min 2: 53 percent / conc. H2SO4 / 20 h / -25 - 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 2 p. 391 - 401
反应条件
1: 1.) conc. H2SO4 / 1.) ether, 2.) RT, 26 h 2: 78 percent / H2SO4 / dioxane / 20 h / Ambient temperature View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 105, # 1-4 p. 129 - 144
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Roeske,R.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1251 - 1253
反应条件
1: Et3N / dioxane / 0 °C 2: 100 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Adlington, Robert M.; Baldwin, Jack E.; Catterick, David; Pritchard, Garcth J.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 8 p. 855 - 866
