hydrogen; palladium on activated charcoal in methanol P=517.1 Torr; Yield given;

1: 79 percent / dicyclohexylcarbodiimide / tetrahydrofuran / Ambient temperature 2: 1.) LDA / 1.) THF, -78 deg C, 15 min, 2.) THF, a) -78 deg C, 0.5 h, b) RT, 1,5 h 3: aq. HCl / acetone / 6 h / Ambient temperature 4: H2 / 10percent Pd/C / methanol / 517.1 Torr View Scheme

1: 1.) LDA / 1.) THF, -78 deg C, 15 min, 2.) THF, a) -78 deg C, 0.5 h, b) RT, 1,5 h 2: aq. HCl / acetone / 6 h / Ambient temperature 3: H2 / 10percent Pd/C / methanol / 517.1 Torr View Scheme

1: 1.) LDA / 1.) THF, -78 deg C, 15 min, 2.) THF, a) -78 deg C, 0.5 h, b) RT, 1,5 h 2: aq. HCl / acetone / 6 h / Ambient temperature 3: H2 / 10percent Pd/C / methanol / 517.1 Torr View Scheme

1: aq. HCl / acetone / 6 h / Ambient temperature 2: H2 / 10percent Pd/C / methanol / 517.1 Torr View Scheme