1-叔丁氧羰基-吲哚-3-硼酸,频哪醇酯合成路线 （共 9 条）
反应条件
potassium carbonate; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=85°C;
参考文献
US2011/15232 A1, ;
Page/Page column 42-44 ;
反应条件
1: N-Boc-3-iodo-indole With n-butyllithium in tetrahydrofuran T=-78°C; 0.666667 h; Inert atmosphere; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran T=-78 - 20°C; 1.75 h; Inert atmosphere;
参考文献
Watson, Charlotte G.; Aggarwal, Varinder K.
Organic Letters, 2013 , vol. 15, # 6 p. 1346 - 1349
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl in hexane T=60°C; 8 h; Inert atmosphere; regioselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 74, # 23 p. 9199 - 9201
反应条件
1: iodine; potassium hydroxide / N,N-dimethyl-formamide / 0.75 h / 20 °C 2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.5 h / 20 °C 3: tetrakis(triphenylphosphine) palladium(0); triethylamine / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 24 p. 4532 - 4535
反应条件
tetrakis(triphenylphosphine) palladium(0); triethylamine in 1,4-dioxane T=80°C; Masuda borylation; 3 h; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 9 p. 3139 - 3141
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.5 h / 20 °C 2: tetrakis(triphenylphosphine) palladium(0); triethylamine / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 24 p. 4532 - 4535
反应条件
1: pyridine; 4-(N,N-dimethlyamino)pyridine / 24 h / 20 °C 2: bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl / tetrahydrofuran / 24 h / 80 °C / Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 2 p. 540 - 543
反应条件
caesium carbonate in 1,4-dioxane; methanol
T=100°C; Suzuki coupling; 24 h; Inert atmosphere;
参考文献
Tasch, Boris O. A.; Merkul, Eugen; Mueller, Thomas J. J.
European Journal of Organic Chemistry, 2011 , # 24 p. 4532 - 4535
参考文献
Kallepalli, Venkata A.; Shi, Feng; Paul, Sulagna; Onyeozili, Edith N.; Maleczka Jr., Robert E.; Smith III, Milton R.
Journal of Organic Chemistry, 2009 , vol. 74, # 23 p. 9199 - 9201
