water; sodium hydroxide in tetrahydrofuran T=20°C; 1 h;

tetra(n-butyl)ammonium hydroxide in tetrahydrofuran; water T=20°C; 0.166667 h; Catalytic behavior; Reagent/catalystSolventTime;

water; sodium hydroxide in tetrahydrofuran T=20°C; 1 h;

1: T=20°C; Cyclization; 24 h; 2: With pyridine in dichloromethane T=20°C; Elimination; 10 h;

1.1: sodium hydroxide; water / tetrahydrofuran / 1 h / 20 °C 2.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 1 h / 0 - 20 °C 2.2: 15 h / 20 °C 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran; water / 0.02 h / 20 °C View Scheme