(1R)-N-oxyl-1-(N-benzylcarbamoyl)-8-azabicyclo[3.2.1]octane; sodium hydrogencarbonate; sodium bromide in dichloromethane; water T=0°C; Electrochemical reaction; optical yield given as percent eeenantioselective reaction;
1: With palladium diacetate; 1,3-bis-(diphenylphosphino)propane; triethylamine in various solvent(s) T=100°C; Heck reaction; 24 h; 2: With hydrogenchloride Further stages.;
1: With TentaGel-N(R)C(O)CH2C2F4OC2F4SO2F; potassium carbonate in N,N-dimethyl-formamide T=20°C; 2: With formic acid; 1,3-bis-(diphenylphosphino)propane; triethylamine; palladium diacetate in N,N-dimethyl-formamide T=85°C; 2 h; Further stages.;
参考文献
Pan, Yijun; Holmes, Christopher P.
Organic Letters, 2001 , vol. 3, # 17 p. 2769 - 2770
