2-甲基-1,3-二氧戊环-2-丙酸乙酯合成路线 （共 17 条）
反应条件
trimethylsilyl trifluoromethanesulfonate in dichloromethane T=-78°C; 4.5 h;
参考文献
THE UNIVERSITY OF BRITISH COLUMBIA
Patent: WO2004/54957 A2, 2004 ;
Location in patent: Page 23-24 ;
反应条件
toluene-4-sulfonic acid in benzene 18 h; Heating;
参考文献
Ogura, Tetsuhiro; Usuki, Toyonobu
Tetrahedron, 2013 , vol. 69, # 13 p. 2807 - 2815
反应条件
ethylene glycol; benzenesulfonic Acid; benzene Entfernen des entstehenden Wassers;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 156, p. 103,137
反应条件
trifluorormethanesulfonic acid in tetrahydrofuran
参考文献
Kanemasa; Otsuka; Doi; Tsuge; Wada
Synthesis, 1990 , # 12 p. 1167 - 1169
反应条件
toluene-4-sulfonic acid Entfernen des entstehenden Butanons;
参考文献
Journal of the Chemical Society, , p. 3972,3978
反应条件
1: aqueous methanol. NaOH-solution 2: diethyl ether View Scheme
参考文献
Warren; Weedon
Journal of the Chemical Society, 1958 , p. 3972,3978
反应条件
1: LiAlH4 / tetrahydrofuran / 6 h / Heating 2: NaH / tetrahydrofuran / 3 h 3: PTSA / methanol / 3 h View Scheme
参考文献
Gurjar, M. K.; Saha, U. K.
Tetrahedron Letters, 1993 , vol. 34, # 11 p. 1833 - 1836
反应条件
1: LiAlH4 / tetrahydrofuran / Ambient temperature 2: pyridine / 18 h / Ambient temperature 3: 1.) K2CO3 / 1.) DMF, 120 deg C, 1 h, 2.) DMF, 120 deg C 4: HCl, MeOH / Ambient temperature View Scheme
参考文献
Cavallaro, Rosaria A.; Filocamo, Luigi; Galuppi, Annamaria; Galione, Antony; Brufani, Mario; Genazzani, Armando A.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 14 p. 2527 - 2534
反应条件
1: 82 percent / 1.) LDA / 1.) THF-hexane, -78 deg C, 2.) RT, 15 h 2: tetrahydrofuran / 72 h / Heating 3: 0.47 g / KF / methanol / 10 h View Scheme
参考文献
Lopez-Cepero, Ingrid Montes de; Santiago, Angel; Larson, Gerald L.
Synthetic Communications, 1986 , vol. 16, # 6 p. 705 - 712
反应条件
diisobutylaluminium hydride in dichloromethane
T=-78°C;
参考文献
Wanner, Martin J.; Boots, Rowan N.A.; Eradus, Bram; De Gelder, Rene; Van Maarseveen, Jan H.; Hiemstra, Henk
Organic Letters, 2009 , vol. 11, # 12 p. 2579 - 2581
