(E)-3-[3-(4-氟苯基)-1-异丙基吲哚-2-基]丙烯醛合成路线 （共 11 条）
反应条件
1: acetoacetic acid tert-butyl ester With n-butyllithium; sodium hydride in tetrahydrofuran; hexane; paraffin oil
T=0 - 25°C;
2: 3-lt;3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-ylgt;-2(E)-propenal in tetrahydrofuran; hexane; paraffin oil
T=0°C; 1.5 h;
3: benzaldehyde in tetrahydrofuran; hexane; paraffin oil
T=0°C; 1 h;
参考文献
Fuenfschilling, Peter C.; Hoehn, Pascale; Mutz, Jean-Paul
Organic Process Research and Development, 2007 , vol. 11, # 1 p. 13 - 18
