反式-2-苯基环丙烷-1-羧酸合成路线 （共 31 条）
反应条件
ethanol; potassium hydroxide T=20°C;
参考文献
Binda, Claudia; Valente, Sergio; Romanenghi, Mauro; Pilotto, Simona; Cirilli, Roberto; Karytinos, Aristotele; Ciossani, Giuseppe; Botrugno, Oronza A.; Forneris, Federico; Tardugno, Maria; Edmondson, Dale E.; Minucci, Saverio; Mattevi, Andrea; Mai, Antonello
Journal of the American Chemical Society, 2010 , vol. 132, # 19 p. 6827 - 6833
反应条件
sodium hydroxide; sodium hypochlorite in acetonitrile T=20°C; 2.5 h;
参考文献
Cooke, Manning P.; Jaw, John Yan
Journal of Organic Chemistry, 1986 , vol. 51, # 5 p. 758 - 760
反应条件
samarium in tetrahydrofuran 1 h; sonication;
参考文献
Concellon, Jose M.; Rodriguez-Solla, Humberto; Simal, Carmen
Organic Letters, 2007 , vol. 9, # 14 p. 2685 - 2688
反应条件
potassium tert-butylate in diethyl ether; water
参考文献
Rodriques, Karen E.
Tetrahedron Letters, 1991 , vol. 32, # 10 p. 1275 - 1278
反应条件
sodium hydroxide in methanol 2 h; Ambient temperature; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1485 - 1493
反应条件
1: Pd(II) 2: aq. LiOH / methanol View Scheme
参考文献
Organic Letters, , vol. 3, # 17 p. 2785 - 2788
反应条件
sodium hydroxide in ethanol
参考文献
Youssef, Abdel-Hamid A.; Sharaf, Saber M.; Abdel-Baki, Samy A.
Journal fuer Praktische Chemie (Leipzig), 1982 , vol. 324, # 3 p. 491 - 497
参考文献
Journal of the American Chemical Society, , vol. 79, p. 401,405
反应条件
1: triethylamine / CH2Cl2 / 3 h / 20 °C 2: 98 percent / KOH; hydrazine hydrate / ethane-1,2-diol / 30 h / 160 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 21 p. 3923 - 3932
反应条件
1: Pd(OAc)2 / diethyl ether; CH2Cl2 / 1.5 h / -10 °C 2: 2 M aq. NaOH / methanol / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1485 - 1493
