(R)-(-)-2-苯基丁酸合成路线 （共 45 条）
参考文献
Phytochemistry (Elsevier), , vol. 21, # 3 p. 782 - 784
反应条件
palladium on carbon; hydrogen in tetrahydrofuran T=20°C; P=760.051 Torr; 24 h;
参考文献
Nakata, Kenya; Onda, Yu-Suke; Ono, Keisuke; Shiina, Isamu
Tetrahedron Letters, 2010 , vol. 51, # 43 p. 5666 - 5669
反应条件
C32H12BF24(1-)*C54H71IrNP(1+); hydrogen; caesium carbonate in methanol T=45°C; P=4560.31 Torr; 12 h; Autoclave; optical yield given as percent eeenantioselective reaction;
参考文献
Zhu, Shou-Fei; Yu, Yan-Bo; Li, Shen; Wang, Li-Xin; Zhou, Qi-Lin
Angewandte Chemie - International Edition, 2012 , vol. 51, # 35 p. 8872 - 8875
参考文献
McCague, Raymond; Leclercq, Guy
Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1761 - 1767
反应条件
C32H12BF24(1-)*C40H44IrNOP(1+); hydrogen; triethylamine in methanol T=30 - 50°C; P=22801.5 Torr; 20 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 46, # 1 p. 156 - 158
反应条件
(-)-(S)-β-Np-BTM; trimethylacetic anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Inert atmosphereResolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 132, # 33 p. 11629 - 11641
反应条件
1: With (R)-BINOL-SnCl4 in dichloromethane; toluene T=-78°C; enantioselective protonation; 1 h; 2: With hydrogenchloride in dichloromethane; toluene Hydrolysis; Further stages. Title compound not separated from byproducts.;
参考文献
Journal of the American Chemical Society, , vol. 122, # 34 p. 8120 - 8130
反应条件
benzoic acid anhydride; N-ethyl-N,N-diisopropylamine; Birman's catalyst in dichloromethane T=20°C; 6 h; Resolution of racemate; Product distribution / selectivity;
参考文献
US2010/234610 A1, ;
Page/Page column 8-10 ;
反应条件
1: 92 percent / LiCl, diisopropylamine, n-BuLi / tetrahydrofuran; hexane / 0 °C 2: aq. 18 N H2SO4 / dioxane / 1.5 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 28 p. 6496 - 6511
参考文献
Lemaire, M.; Delabouglise, D.; Garreau, R.; Roncali, J.
Journal de Chimie Physique et de Physico-Chimie Biologique, 1989 , vol. 86, # 1 p. 193 - 198
