2,2,2-三甲基苯乙酮合成路线 （共 203 条）
反应条件
tributylphosphine in tetrahydrofuran T=20°C; 1 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 50, # 13 p. 1501 - 1503
参考文献
Journal of the American Chemical Society, , vol. 104, # 21 p. 5824 - 5826
反应条件
polymeric trityllithium 1) THF; Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 103, # 25 p. 7620 - 7629
反应条件
3,3-dimethyldioxirane in dichloromethane T=-20 - 20°C; 5 h; Further byproducts given;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 75, # 2 p. 319 - 328
反应条件
1: 11 percent / sulfur / various solvent(s) / 144 h / 20 °C 2: 9 percent Spectr. / dimethyldioxirane / CH2Cl2 / 5 h / -20 - 20 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 75, # 2 p. 319 - 328
反应条件
1: 56 percent / pentane / 1.) ice bath, 2.) reflux, 4 h 2: aq. hydrochloric acid / diethyl ether View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 23 p. 4349 - 4357
反应条件
diethyl ether T=-78°C;
参考文献
Journal of Organic Chemistry, , vol. 6, p. 462,464
反应条件
aluminium trichloride
参考文献
Journal of the American Chemical Society, , vol. 63, p. 2511
反应条件
LiDBB 1.) THF, -65 to -55 deg C, 45 min, 2.) a) ether, -78 deg C, b) RT, 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 112, # 6 p. 2194 - 2216
反应条件
1: LDA 2: NaOH 3: 75 percent / O2, pivalaldehyde, (NMe4)<CoL>*2H2O*CH3CN (L = ortho-phenylenebis(N'-methyloxamidate)) / acetonitrile / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 20 p. 3327 - 3330
