1: mono-methyl malonate potassium salt With triethylamine; magnesium chloride in acetonitrile 1 h; 2: 3-trifluoromethyl-benzoyl chloride in acetonitrile T=10 - 20°C; Cooling with ice;

potassium methanolate in iso-xylene T=80°C; P=760.051 Torr; 12 h; Industry scale; Product distribution / selectivity;

sodium hydride in various solvent(s) Heating;

sodium hydrogencarbonate; ammonium chloride in ethanol Reflux;