1.1: p-TsCl; pyridine / 24 h / 80 °C 2.1: D2O / diethyl ether / 0.02 h / -78 °C 3.1: LDA / tetrahydrofuran / 0.02 h / -100 °C 3.2: D2O / diethyl ether View Scheme

1: p-TsCl; pyridine / 24 h / 80 °C 2: n-BuLi / diethyl ether / 1 h / -100 °C View Scheme