sodium dithionite; 1,1'-di-n-octyl-4,4'-bipyridinium dibromide in water; ethyl acetate Yield given;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102438', constants.ctx, '0')">piperidine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />4&nbsp;h;&nbsp;&nbsp;Inert atmosphereMolecular sieveReflux;&nbsp;&nbsp;stereoselective reaction;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: aq. NaOH / methanol / 12 h / 20 &deg;C<br />2: CH₂Cl₂ / 20 h / Heating<br /> <br /> &nbsp;