N-(5-甲基-2-苯基吡咯基)-4 吡啶羧酰胺合成路线 （共 6 条）
反应条件
toluene-4-sulfonic acid in dichloromethane
T=40 - 50°C; 2 - 3 h; Heating / reflux;
参考文献
LUPIN LIMITED
Patent: WO2006/109323 A1, 2006 ;
Location in patent: Page/Page column 15-16 ;
反应条件
molecular sieve in benzene
2 h; Heating / reflux;
参考文献
LUPIN LIMITED
Patent: WO2004/26828 A1, 2004 ;
Location in patent: Page 25 ;
反应条件
in benzene
2 h; Heating / refluxMolecular sieve;
参考文献
LUPIN LTD
Patent: US2005/256128 A1, 2005 ;
Location in patent: Page/Page column 11 ;
反应条件
1: With formaldehyd; acetic acid in acetonitrile
T=20°C; 4 h;
2: With sodium hydroxide in water; acetonitrile
参考文献
LUPIN LTD
Patent: US2005/256128 A1, 2005 ;
Location in patent: Page/Page column 11 ;
反应条件
1: With acetic acid in water; acetonitrile
T=20°C; 4 h;
2: With sodium hydroxide in water; acetonitrile
参考文献
LUPIN LIMITED
Patent: WO2004/26828 A1, 2004 ;
Location in patent: Page 25-26 ;
反应条件
1: With acetic acid in acetonitrile
T=25 - 30°C; 15 - 17.5 h;
2: With sodium hydroxide in water; acetonitrile
参考文献
LUPIN LIMITED
Patent: WO2006/109323 A1, 2006 ;
Location in patent: Page/Page column 16-18 ;
