carbon monoxide; triphenylphosphine; palladium diacetate in acetonitrile P=3040 Torr; 75 h; Heating;

hydrogen; palladium on activated charcoal in tetrahydrofuran 1 h;

1,1'-bis-(diphenylphosphino)ferrocene; triethylamine; dichloro bis(acetonitrile) palladium(II) T=130°C; P=51714.8 Torr; 48 h;

1: With sulfuric acid 20 h; Reflux; 2: With sodium hydrogencarbonate in ethyl acetate

1: 72 percent / tetrahydrofuran / 25 h / -45 - -40 °C 2: 80 percent / triethylamine; dppf / Pd(CH3CN)2Cl2 / 48 h / 130 °C / 51714.8 Torr View Scheme

1: 55 percent / dibenzoyl peroxide, NBS / CCl4 / 23.5 h / 90 °C / Irradiation 2: 75 percent / CHCl3 / 0.25 h / Heating 3: 100 percent / Et3N / CH2Cl2 / 0.08 h / Ambient temperature 4: 71 percent / PPh3, CO / Pd(OAc)2 / acetonitrile / 75 h / 3040 Torr / Heating View Scheme

1: 75 percent / CHCl3 / 0.25 h / Heating 2: 100 percent / Et3N / CH2Cl2 / 0.08 h / Ambient temperature 3: 71 percent / PPh3, CO / Pd(OAc)2 / acetonitrile / 75 h / 3040 Torr / Heating View Scheme

1: HCl / 6 h / 80 °C 2: dimethylformamide / 6.5 h / 100 °C 3: H2 / 5percent Pd/C View Scheme

1: 75 percent / tri-o-tolylphosphine, triethylamine / palladium(II) acetate / acetonitrile / 24 h / 120 °C / 22800 Torr 2: 74 percent / oxygen / palladium(II) chloride, copper(I) chloride / 1,2-dimethoxy-ethane / 24 h / 50 - 60 °C 3: 1.) H2, 2.) aq. HCl / 10percent rhodium-carbon / 1.) ethanol, room temperature, 1 atmosphere, 3 h, 2.) room temperature, 3 h View Scheme

hydrogenchloride; hydrogen; rhodium contaminated with carbon 1.) ethanol, room temperature, 1 atmosphere, 3 h, 2.) room temperature, 3 h; Yield given. Multistep reaction;