5-(2-氯-乙酰基)-1,3-二氢-苯并咪唑-2-酮合成路线 （共 2 条）
反应条件
1: chloroacetyl chloride With AlCl3, aluminium chloride in 1,2-dichloro-ethane
T=0°C; Friedel Crafts Acylation; 0.5 h;
2: 2-Hydroxy-1H-benzimidazole in 1,2-dichloro-ethane
T=20 - 55°C; 18 h;
参考文献
CORTICAL PTY LTD
Patent: WO2007/70961 A1, 2007 ;
Location in patent: Page/Page column 56 ;
反应条件
aluminium trichloride in 1,1,2,2-tetrachloroethylene
T=90 - 100°C; 1 h;
参考文献
Kadyrov, Ch. Sh.; Khalikov, S. S.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 6 p. 658 - 661
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 6 p. 808 - 811
