2-氨甲酰吡咯烷-1-羧酸苄酯合成路线 （共 7 条）
反应条件
1: With 4-methyl-morpholine in dichloromethane T=0°C; 0.166667 h; 2: With chloroformic acid ethyl ester in dichloromethane T=-15°C; 2 h; 3: With ammonia in dichloromethane T=-20 - 0°C; 1 h;
参考文献
Kalypsys, Inc.
Patent: US2006/116515 A1, 2006 ;
Location in patent: Page/Page column 66 ;
US 20060116515 A1
参考文献
Journal of Biological Chemistry, , vol. 193, p. 81,87
反应条件
sodium; ammonium chloride in ammonia
参考文献
Schoen, Istvan; Szirtes, Tamas; Ueberhardt, Tamas
Journal of the Chemical Society, Chemical Communications, 1982 , # 11 p. 639 - 640
反应条件
hydrogen; palladium on activated charcoal in methanol P=2068.6 Torr; 5 h;
参考文献
Rispens, Minze T.; Gelling, Onko Jan; De Vries, Andre H.M.; Meetsma, Auke; Van Bolhuis, Fre; Feringa, Ben L.
Tetrahedron, 1996 , vol. 52, # 10 p. 3521 - 3546
反应条件
sodium; ammonium chloride in ammonia
参考文献
Schoen, Istvan; Szirtes, Tamas; Ueberhardt, Tamas
Journal of the Chemical Society, Chemical Communications, 1982 , # 11 p. 639 - 640
反应条件
in pyridine; dichloromethane T=-10°C; 2.66667 h;
参考文献
Kalypsys, Inc.
Patent: US2006/116515 A1, 2006 ;
Location in patent: Page/Page column 66 ;
US 20060116515 A1
反应条件
1: H2 / 5percent Pd/C / methanol / 5 h / 2068.6 Torr
2: CH2Cl2; methanol / 16 h
3: 1.) LiAlH4, 2.) aq. KOH / tetrahydrofuran / 16 h
View Scheme
参考文献
Rispens, Minze T.; Gelling, Onko Jan; De Vries, Andre H.M.; Meetsma, Auke; Van Bolhuis, Fre; Feringa, Ben L.
Tetrahedron, 1996 , vol. 52, # 10 p. 3521 - 3546
