1.1: CrCl2 / tetrahydrofuran; dioxane / 0 °C 2.1: N-methylpyrrolidinone; [Pd{P(2-furyl)3}2Cl2]; hexamethyltin / 20 °C 2.2: [Pd{P(2-furyl)3}2Cl2]; N-methylpyrrolidinone / 20 °C 3.1: 81 percent / LiAlH(OtBu)3 / tetrahydrofuran / -10 °C 4.1: 81 percent / 4-pyrrolidinopyridine / CH2Cl2 5.1: 89 percent / lithium hydroxide / H2O; tetrahydrofuran / 0 °C 6.1: 88 percent / 2,6-lutidine / CH2Cl2 / -20 - 20 °C 7.1: 66 percent / 2,6-lutidine / CH2Cl2 / -20 °C 8.1: 88 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH2Cl2 / 0 - 20 °C 9.1: 81 percent / potassium carbonate / dimethylformamide / 20 °C 10.1: 78 percent / lithium bis(trimethylsilyl)amide / tetrahydrofuran / -78 - -20 °C 11.1: 80 percent / dimedone / [Pd(PPh3)4] / tetrahydrofuran / 20 °C 12.1: PhI(OAc)2 / acetonitrile; H2O / 0 °C 13.1: 2,9-dimethyl-1,10-phenanthroline; pyridine / CH2Cl2 / 20 °C 14.1: 61 percent / pyridine*HF / tetrahydrofuran / 50 °C View Scheme