1-苯基-1,3-丁二酮合成路线 （共 471 条）
反应条件
hydrogenchloride in ethanol
4 h; Heating;
参考文献
George, Sumod; Nangia, Ashwini; Bagieu-Beucher, Muriel; Masse, Rene; Nicoud, Jean-Francois
New Journal of Chemistry, 2003 , vol. 27, # 3 p. 568 - 576
反应条件
ethylmagnesium bromide
1.) ether, 2.) toluene, 80 deg C, 5 hours; Yield given. Multistep reaction;
参考文献
Sartori, Giovanni; Maggi, Raimondo; Bigi, Franca; Porta, Cecilia; Tao, Xiaochun; Bernardi, Gian Luca; Ianelli, Sandra; Nardelli, Mario
Tetrahedron, 1995 , vol. 51, # 44 p. 12179 - 12192
反应条件
aluminium trichloride
1) nitromethane, r.t., 15 min, 2a) nitromethane, r.t., 15 min, 2b) 80 deg C, 1-2 h; Yield given. Multistep reaction;
参考文献
Sartori, Giovanni; Bigi, Franca; Tao, Xiaochun; Casnati, Giuseppe; Canali, Giacomo
Tetrahedron Letters, 1992 , vol. 33, # 33 p. 4771 - 4774
反应条件
hydrogenchloride; trans-[Pt(μ-Cl)Cl(C2H4)]2 in 1,4-dioxane
T=90°C; P=2585.81 Torr;
参考文献
Wang, Xiang; Widenhoefer, Ross A.
Chemical Communications, 2004 , # 6 p. 660 - 661
反应条件
sodium hydride in dimethyl sulfoxide
参考文献
Gree, Rene; Park, Hokoon; Paquette, Leo A.
Journal of the American Chemical Society, 1980 , vol. 102, # 13 p. 4397 - 4403
反应条件
ethanol; sodium ethanolate
参考文献
Bowden
Journal of the American Chemical Society, 1938 , vol. 60, p. 131
反应条件
sodium; benzene
Erhitzen des ausgeschiedenen Salzes mit Aethyljodid;
参考文献
Claisen; Lowman
Chemische Berichte, 1888 , vol. 21, p. 1152 Anm. 2
反应条件
chloroform; tris-(2-chloro-ethyl)-amine; sulfuric acid
参考文献
Caronna
Gazzetta Chimica Italiana, 1950 , vol. 80, p. 217
参考文献
Dale; Strobel
Journal of the American Chemical Society, 1954 , vol. 76, p. 6172
反应条件
1: 1-phenylbutane-1,3-dione With lithium diisopropyl amide in tetrahydrofuran
T=-70 - -20°C;
2: ethyl iodide in tetrahydrofuran
T=-20 - 20°C;
3: With hydrogenchloride in tetrahydrofuran; water
pH=4 - 5;
参考文献
Sams, Anette Graven; Mikkelsen, Gitte Kobberoe; Larsen, Mogens; Torup, Lars; Brennum, Lise Tottrup; Schroder, Tenna Juul; Bang-Andersen, Benny
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 17 p. 5241 - 5244
