5-(3-氯苯基)呋喃-2-甲酰氯合成路线 （共 7 条）
反应条件
thionyl chloride in benzene Reflux;
参考文献
Gorak; Obushak; Matiichuk; Lytvyn
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 4 p. 541 - 550
反应条件
1: Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane / 100 °C 2: aq. LiOH / tetrahydrofuran 3: (COCl)2 / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3258 - 3261
反应条件
1: Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane / 100 °C 2: aq. LiOH / tetrahydrofuran 3: (COCl)2 / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3258 - 3261
反应条件
1: aq. LiOH / tetrahydrofuran 2: (COCl)2 / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3258 - 3261
反应条件
1: hydrogenchloride; sodium nitrite 2: thionyl chloride / benzene / 3 h / Reflux View Scheme
参考文献
Chemical Biology and Drug Design, , vol. 79, # 1 p. 121 - 127
反应条件
1: hydrogenchloride; sodium nitrite 2: thionyl chloride / benzene / 3 h / Reflux View Scheme
参考文献
Chemical Biology and Drug Design, , vol. 79, # 1 p. 121 - 127
反应条件
1: 93 percent / triethylamine / CHCl3 / 1.) -5 to 0 deg C, 30 min; 2.) r.t., 1 h
2: PCl5 / benzene / 0.25 h / 75 °C
3: sodium azide / dimethylformamide / 0.5 h
4: 1.) 3M KOH, 2.) 15percent HCl / methanol; H2O / 1 h / Heating
View Scheme
参考文献
Janda; Voticky; Svetlik; et al.
Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 6 p. 1505 - 1514
