2,4-二氯噻唑-5-甲醛合成路线 （共 12 条）
反应条件
trichlorophosphate 1) RT, 1h, 2) 80 to 90 deg C, 1h, 3) 115 deg C, 4h;
参考文献
Athmani, Salah; Farhat, Mahmoud F.; Iddon, Brian
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 8 p. 973 - 978
反应条件
trichlorophosphate in N,N-dimethyl-formamide
反应条件
in N,N-dimethyl-formamide
参考文献
Cai, Sui Xiong; Zhang, Han-Zhong; Drewe, John A.; Reddy, P. Sanjeeva; Kasibhatla, Shailaja; Kuemmerle, Jared Daniel; Ollis, Kristin P.
Patent: US2003/45546 A1, 2003 ;
US 20030045546 A1
反应条件
hydrogenchloride; n-butyllithium 1) hexane, THF, -78 deg C, 10 min., 2) THF, up to room temp., 2h; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 2 p. 329 - 331
反应条件
in tetrachloromethane T=20°C;
参考文献
Kotlyar; Pushkarev; Orlov; Chernenko; Desenko
Chemistry of Heterocyclic Compounds, 2010 , vol. 46, # 3 p. 334 - 341
反应条件
hydrogen; sodium acetate; palladium on activated charcoal in methanol T=55°C; 15 h;
参考文献
Kerdesky; Seif
Synthetic Communications, 1995 , vol. 25, # 24 p. 4081 - 4086
反应条件
in tetrachloromethane
参考文献
Kotlyar; Pushkarev; Orlov; Chernenko; Desenko
Chemistry of Heterocyclic Compounds, 2010 , vol. 46, # 3 p. 334 - 341
反应条件
potassium carbonate in acetonitrile 12 h; Ambient temperature;
参考文献
Debski, Norbert; Hanefeld, Wolfgang; Schlitzer, Martin
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1427 - 1429
反应条件
sodium tetrahydroborate in methanol T=23°C; 2 h;
参考文献
Kerdesky; Seif
Synthetic Communications, 1995 , vol. 25, # 17 p. 2639 - 2645
反应条件
sodium chlorite; aminosulfonic acid; water in tetrahydrofuran T=20°C; 2 h;
参考文献
Hasegawa, Masaichi; Kano, Kazuya; Nakano, Masato; Yamabe, Mariko
Patent: US2009/270456 A1, 2009 ;
Location in patent: Page/Page column 8 ;
