ammonia in methanol T=20°C; 144 h;

1: 78 percent / 3 h / Temperature: from -20 deg C to room temp. 2: pyridinium p-toluenesulfonate / CH2Cl2 / 24 h / Ambient temperature 3: HF*Pyr / tetrahydrofuran / 24 h / Ambient temperature 4: 4 h / Ambient temperature 5: 70 percent / pyridine; CH2Cl2 / 4 h / Temperature: from -20 deg C to 0 deg C 6: 97 percent / hexamethylphosphoric acid triamide; dimethylformamide / 20 h / Ambient temperature 7: 1.) NH3, 2.) aq. acetic acid / 1.) methanol, room temp., 2.) room temp. View Scheme

1: 4 h / Ambient temperature 2: 70 percent / pyridine; CH2Cl2 / 4 h / Temperature: from -20 deg C to 0 deg C 3: 97 percent / hexamethylphosphoric acid triamide; dimethylformamide / 20 h / Ambient temperature 4: 1.) NH3, 2.) aq. acetic acid / 1.) methanol, room temp., 2.) room temp. View Scheme

1: pyridinium p-toluenesulfonate / CH2Cl2 / 24 h / Ambient temperature 2: HF*Pyr / tetrahydrofuran / 24 h / Ambient temperature 3: 4 h / Ambient temperature 4: 70 percent / pyridine; CH2Cl2 / 4 h / Temperature: from -20 deg C to 0 deg C 5: 97 percent / hexamethylphosphoric acid triamide; dimethylformamide / 20 h / Ambient temperature 6: 1.) NH3, 2.) aq. acetic acid / 1.) methanol, room temp., 2.) room temp. View Scheme

1: HF*Pyr / tetrahydrofuran / 24 h / Ambient temperature 2: 4 h / Ambient temperature 3: 70 percent / pyridine; CH2Cl2 / 4 h / Temperature: from -20 deg C to 0 deg C 4: 97 percent / hexamethylphosphoric acid triamide; dimethylformamide / 20 h / Ambient temperature 5: 1.) NH3, 2.) aq. acetic acid / 1.) methanol, room temp., 2.) room temp. View Scheme

1: 70 percent / pyridine; CH2Cl2 / 4 h / Temperature: from -20 deg C to 0 deg C 2: 97 percent / hexamethylphosphoric acid triamide; dimethylformamide / 20 h / Ambient temperature 3: 1.) NH3, 2.) aq. acetic acid / 1.) methanol, room temp., 2.) room temp. View Scheme

1: 97 percent / hexamethylphosphoric acid triamide; dimethylformamide / 20 h / Ambient temperature 2: 1.) NH3, 2.) aq. acetic acid / 1.) methanol, room temp., 2.) room temp. View Scheme

ammonia; acetic acid 1.) methanol, room temp., 2.) room temp.; Yield given. Multistep reaction;