oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78°C;

lithium hydroxide hydrate in tetrahydrofuran; methanol T=20°C;

1.1: triethylamine / acetone / 3 h / 20 °C / Large scale reaction 1.2: 1 h / Reflux; Large scale reaction 2.1: sulfuric acid / 6 h / 60 °C / Large scale reaction 3.1: 15 - 30 °C 4.1: 16 h / 30 °C / 3345.86 Torr 6.1: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme

1: sulfuric acid / 6 h / 60 °C / Large scale reaction 2: 15 - 30 °C 3: 16 h / 30 °C / 3345.86 Torr 5: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme

1: 180 °C / open vessel 2: 15 - 30 °C 3: 16 h / 30 °C / 3345.86 Torr 5: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme

1.1: acetic anhydride / acetic acid / 2 h / Reflux; Large scale reaction 2.1: triethylamine / acetone / 3 h / 20 °C / Large scale reaction 2.2: 1 h / Reflux; Large scale reaction 3.1: sulfuric acid / 6 h / 60 °C / Large scale reaction 4.1: 15 - 30 °C 5.1: 16 h / 30 °C / 3345.86 Torr 7.1: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme

1.1: sodium hydroxide / ethanol / 50 °C / Reflux; Large scale reaction 2.1: acetic anhydride / acetic acid / 2 h / Reflux; Large scale reaction 3.1: triethylamine / acetone / 3 h / 20 °C / Large scale reaction 3.2: 1 h / Reflux; Large scale reaction 4.1: sulfuric acid / 6 h / 60 °C / Large scale reaction 5.1: 15 - 30 °C 6.1: 16 h / 30 °C / 3345.86 Torr 8.1: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme

2: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme

1: 16 h / 30 °C / 3345.86 Torr 3: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme

1: 15 - 30 °C 2: 16 h / 30 °C / 3345.86 Torr 4: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / -78 °C View Scheme