1: With lithium aluminium tetrahydride in tetrahydrofuran
T=5°C; 1 h;
2: With ethyl acetate in tetrahydrofuran
3: With water in tetrahydrofuran; dichloromethane; ethyl acetate
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/84223 A2, 2008 ;
Location in patent: Page/Page column 424 ;
WO 2008/084223 A2
