苄基2,3-二乙酰氧基-1-哌啶羧酸酯合成路线 （共 5 条）
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine
T=20°C; 3 h;
参考文献
Okitsu; Suzuki; Kobayashi
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 809 - 823
反应条件
1: 5.34 g / H2SO4 / tetrahydrofuran / 1 h / 20 °C
2: 76 percent / oxone(R); K2CO3 / H2O; acetone / 2 h / 20 °C
3: 88 percent / DMAP; Et3N / 2 h / 20 °C
View Scheme
参考文献
Takeuchi, Yasuo; Azuma, Kumiko; Oshige, Miyo; Abe, Hitoshi; Nishioka, Hiromi; Sasaki, Kenji; Harayama, Takashi
Tetrahedron, 2003 , vol. 59, # 10 p. 1639 - 1646
反应条件
1: NaBH4 / methanol / 0.25 h / 0 °C
2: 5.34 g / H2SO4 / tetrahydrofuran / 1 h / 20 °C
3: 76 percent / oxone(R); K2CO3 / H2O; acetone / 2 h / 20 °C
4: 88 percent / DMAP; Et3N / 2 h / 20 °C
View Scheme
参考文献
Takeuchi, Yasuo; Azuma, Kumiko; Oshige, Miyo; Abe, Hitoshi; Nishioka, Hiromi; Sasaki, Kenji; Harayama, Takashi
Tetrahedron, 2003 , vol. 59, # 10 p. 1639 - 1646
反应条件
1: 76 percent / oxone(R); K2CO3 / H2O; acetone / 2 h / 20 °C
2: 88 percent / DMAP; Et3N / 2 h / 20 °C
View Scheme
参考文献
Takeuchi, Yasuo; Azuma, Kumiko; Oshige, Miyo; Abe, Hitoshi; Nishioka, Hiromi; Sasaki, Kenji; Harayama, Takashi
Tetrahedron, 2003 , vol. 59, # 10 p. 1639 - 1646
反应条件
sodium hydrogencarbonate
1.) anodic oxidation, AcOH, 2.) H2O,; Yield given. Multistep reaction;
参考文献
Shono, Tatsuya; Matsumura, Yoshihiro; Onomura, Osamu; Kanazawa, Takenobu; Habuka, Masahiro
Chemistry Letters, 1984 , p. 1101 - 1104
