1: methanolic sodium methoxide / benzene 2: Et3N / CHCl3 / 100 °C / sealed tube View Scheme

<b>Multi-step reaction with 11 steps<br /> </b>1: 78 percent / Ac₂O, pyridine<br />2: 95 percent / Et₃N<br />3: 98 percent / 10 percent HCl / tetrahydrofuran<br />4: HN(SiMe₃)2<br />6: DBU / 2-methyl-propan-2-ol / Heating<br />7: H₂ / Raney Ni<br />8: 80 percent / Mg(OTf)2<br />9: 73 percent / CHCl₃ <br />10: 1.) Et₃O⁽¹⁺⁾*BF₄^(1-), Na₂CO₃; 2.) HOAc / 1.) THF, CH₂Cl₂ <br />11: 80 percent / ethanol<br /> <br /> &nbsp;