3-二甲氨基-2-甲酰基丙烯酸乙酯合成路线

6148-64-7丙二酸单乙酯钾盐+68-12-2N,N-二甲基甲酰胺→92385-43-83-二甲氨基-2-甲酰基丙烯酸乙酯

参考文献

Collection of Czechoslovak Chemical Communications, , vol. 26, p. 3051 - 3058

92385-43-83-二甲氨基-2-甲酰基丙烯酸乙酯+354-37-0三氟乙脒→304693-64-92-三氟甲基嘧啶-5-羧酸乙酯

参考文献

Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto
Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004

1670-14-0苄脒盐酸盐+92385-43-83-二甲氨基-2-甲酰基丙烯酸乙酯→85386-14-7乙基 2-苯基嘧啶-5-羧酸

参考文献

Signal Pharmaceuticals, Inc.
Patent: US5811428 A1, 1998 ;

92385-43-83-二甲氨基-2-甲酰基丙烯酸乙酯+100-63-0苯肼→885-94-91-苯基-1H-吡唑-4-羧酸乙酯

参考文献

Subasinghe, Nalin L.; Ali, Farah; Illig, Carl R.; Rudolph, M. Jonathan; Klein, Scott; Khalil, Ehab; Soll, Richard M.; Bone, Roger F.; Spurlino, John C.; DesJarlais, Renee L.; Crysler, Carl S.; Cummings, Maxwell D.; Morris Jr., Philip E.; Kilpatrick, John M.; Babu, Y. Sudhakara
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 12 p. 3043 - 3047

867-44-7S-甲基异硫脲半硫酸盐+92385-43-83-二甲氨基-2-甲酰基丙烯酸乙酯→73781-88-12-甲硫基-5-嘧啶羧酸乙酯

参考文献

Arukwe, Joseph; Undheim, Kjell
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 9 p. 764 - 767

14527-26-52-甲基-2-硫代异脲硫酸盐+92385-43-83-二甲氨基-2-甲酰基丙烯酸乙酯→73781-88-12-甲硫基-5-嘧啶羧酸乙酯

参考文献

Yu-Xiu, Liu; Ming-Bo, Cui; Qi-Qi, Zhao; Qing-Min, Wang; Ying, Liu; Run-Qiu, Huang
Journal of Chemical Research, 2007 , # 8 p. 490 - 493

2986-19-82-甲基-2-疏基硫酸脲+92385-43-83-二甲氨基-2-甲酰基丙烯酸乙酯→73781-88-12-甲硫基-5-嘧啶羧酸乙酯

参考文献

Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto
Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004