2,3,5,6-四氟对苯二甲醇合成路线 （共 31 条）
反应条件
1.1: n-BuLi / tetrahydrofuran / -25 °C 1.2: 76 percent / tetrahydrofuran / -25 - 20 °C 2.1: 72 percent / TFA; aq. HCl / 0.33 h / 55 °C 3.1: 83 percent / (CH3)2S*BH3 / tetrahydrofuran / 0.25 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 120, # 1 p. 77 - 84
反应条件
1: 72 percent / TFA; aq. HCl / 0.33 h / 55 °C 2: 83 percent / (CH3)2S*BH3 / tetrahydrofuran / 0.25 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 120, # 1 p. 77 - 84
反应条件
1.1: n-BuLi / tetrahydrofuran / 0.25 h / -60 °C 1.2: 73 percent / tetrahydrofuran / -60 - 20 °C 2.1: 43 percent / aq. TFA / 2 h / Heating 3.1: 83 percent / (CH3)2S*BH3 / tetrahydrofuran / 0.25 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 120, # 1 p. 77 - 84
反应条件
1: 43 percent / aq. TFA / 2 h / Heating 2: 83 percent / (CH3)2S*BH3 / tetrahydrofuran / 0.25 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 120, # 1 p. 77 - 84
反应条件
hydrogen; sponge cobalt catalyst in water-containing state in toluene T=160°C; P=3975.4 - 165017 Torr; 0.5 - 1 h; Product distribution / selectivity;
参考文献
US2004/10167 A1, ;
Page 3-5 ;
反应条件
potassium hydroxide in water; toluene T=50 - 60°C; 4.5 h; Heating / reflux;
参考文献
US6339176 B2, ;
Page column 5 ;
反应条件
potassium hydroxide; nitrogen; dimethyl sulfate in water; toluene
参考文献
Hirose, Taro; Mori, Tatsuya
Patent: US2001/3138 A1, 2001 ;
反应条件
sodium hydroxide; nitrogen in water; dimethyl sulfate
参考文献
Hirose, Taro; Mori, Tatsuya
Patent: US2001/3138 A1, 2001 ;
反应条件
thionyl chloride 5 h; Heating;
参考文献
Brooke, Gerald M.; Mawson, Simon D.
Journal of Fluorine Chemistry, 1990 , vol. 50, # 1 p. 101 - 109
反应条件
hydrogen bromide in water; toluene
T=90°C; 4 h;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP2123624 A1, 2009 ;
Location in patent: Page/Page column 12-13 ;
