5-溴-2-(三氟甲氧基)苯甲醛合成路线 (共 1 条)
反应条件
1: 1-bromo-4-(trifluoromethoxy)benzene With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-78 - 0°C; 2 h; 2: (4-morpholinyl)methanone in tetrahydrofuran; hexane
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2007/15588 A1, 2007 ;
Location in patent: Page/Page column 83-84 ;
WO 2007/015588 A1