3-甲基-[1,1-联苯]-2-羧酸合成路线 （共 18 条）
反应条件
lithium hydroxide hydrate in tetrahydrofuran; methanol; water T=20°C; 20 h; Inert atmosphere;
参考文献
Gallardo-Donaire, Joan; Martin, Ruben
Journal of the American Chemical Society, 2013 , vol. 135, # 25 p. 9350 - 9353
反应条件
dipotassium hydrogenphosphate; sodium acetate; silver carbonate; palladium diacetate in tert-butyl alcohol
T=130°C; 3 h;
参考文献
Giri, Ramesh; Maugel, Nathan; Li, Jiao-Jie; Wang, Dong-Hui; Breazzano, Steven P.; Saunders, Lindsey B.; Yu, Jin-Quan
Journal of the American Chemical Society, 2007 , vol. 129, # 12 p. 3510 - 3511
反应条件
dipotassium hydrogenphosphate; oxygen; palladium diacetate; p-benozquinone in tert-butyl alcohol
T=100°C; P=22801.5 Torr; 24 h;
参考文献
Wang, Dong-Hui; Mei, Tian-Sheng; Yu, Jin-Quan
Journal of the American Chemical Society, 2008 , vol. 130, # 52 p. 17676 - 17677
反应条件
dipotassium hydrogenphosphate; silver carbonate; p-benozquinone; palladium diacetate in tert-butyl alcohol
T=120°C; 3 h;
参考文献
Giri, Ramesh; Maugel, Nathan; Li, Jiao-Jie; Wang, Dong-Hui; Breazzano, Steven P.; Saunders, Lindsey B.; Yu, Jin-Quan
Journal of the American Chemical Society, 2007 , vol. 129, # 12 p. 3510 - 3511
反应条件
silver carbonate; p-benozquinone; palladium diacetate in tert-butyl alcohol
T=120°C; 3 h;
参考文献
Giri, Ramesh; Maugel, Nathan; Li, Jiao-Jie; Wang, Dong-Hui; Breazzano, Steven P.; Saunders, Lindsey B.; Yu, Jin-Quan
Journal of the American Chemical Society, 2007 , vol. 129, # 12 p. 3510 - 3511
反应条件
potassium hydroxide in ethylene glycol
T=100°C; 8 h;
参考文献
Wasa, Masayuki; Chan, Kelvin S. L.; Yu, Jin-Quan
Chemistry Letters, 2011 , vol. 40, # 9 p. 1004 - 1006
反应条件
palladium diacetate in water
T=100°C; 3 h; Green chemistry; chemoselective reaction;
参考文献
Wu, Zhiqing; Chen, Si; Hu, Chenxu; Li, Zhengkai; Xiang, Haifeng; Zhou, Xiangge
ChemCatChem, 2013 , vol. 5, # 10 p. 2839 - 2842
反应条件
sec.-butyllithium in tetrahydrofuran; cyclohexane
T=-78°C; 2.5 h; Product distribution; Further Variations:ReagentsTemperatures;
参考文献
Tilly, David; Samanta, Subhendu S.; Castanet, Anne-Sophie; De, Asish; Mortier, Jacques
European Journal of Organic Chemistry, 2006 , # 1 p. 174 - 182
反应条件
dinitrogen trioxide in acetic acid
参考文献
Hoover,J.R.E. et al.
J. Med. Chem., 1964 , vol. 7, # 3 p. 245 - 251
反应条件
1: aq. NaOH / ethane-1,2-diol
2: N2O3 / acetic acid
View Scheme
参考文献
Hoover,J.R.E. et al.
J. Med. Chem., 1964 , vol. 7, # 3 p. 245 - 251
