4-溴-7H-吡咯并[2,3-d]嘧啶合成路线 （共 2 条）
反应条件
1: With phosphorus oxytribromide T=70 - 80°C; 2.25 h; 2: With water; sodium hydrogencarbonate T=0°C; pH=~ 8;
参考文献
ALANTOS PHARMACEUTICALS HOLDING, INC.
Patent: WO2008/63669 A1, 2008 ;
Location in patent: Page/Page column 70-71 ;
WO 2008/063669 A1
反应条件
1: With phosphorus oxytribromide
T=70 - 80°C; 2.25 h;
2: With water; sodium hydrogencarbonate
T=0°C; pH=~ 8;
参考文献
ALANTOS PHARMACEUTICALS HOLDING, INC.
Patent: WO2008/63669 A1, 2008 ;
Location in patent: Page/Page column 70-71 ;
WO 2008/063669 A1
