2-(氮杂啶-1-基羰基)-5-溴嘧啶合成路线 （共 2 条）
反应条件
triethylamine in dichloromethane
T=20°C; 72 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/7041 A1, 2007 ;
Location in patent: Page/Page column 113 ;
WO 2007/007041 A1
反应条件
1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 2.5 h / 20 °C / Inert atmosphere
2: triethylamine / dichloromethane / 20 °C
View Scheme
参考文献
PFIZER INC.; ASPNES, Gary Erik; DIDIUK, Mary Theresa; GUZMAN-PEREZ, Angel; MAGUIRE, Robert John
Patent: WO2011/158149 A1, 2011 ;
WO 2011/158149 A1
