1: 88 percent / pyridine / 1 h / 20 °C
2: conc. NH4OH / dioxane / 24 h / 50 °C
View Scheme
参考文献
Roelen, H. C. P. F.; Brugghe, H. F.; Elst, H. van den; Klein, J. C.; Marel, G. A. van der; Boom, J. H. van
Recueil des Travaux Chimiques des Pays-Bas, 1992 , vol. 111, p. 227 - 234
1: 88 percent / pyridine / 1 h / 20 °C
2: conc. NH4OH / dioxane / 24 h / 50 °C
3: N-methylimidazole (NMI) / pyridine / 0.5 h / 20 °C
4: 81 percent / 4-(dimethylamino)pyridine (DMAP), triethylamine / CH2Cl2 / 16 h
5: 71 percent / N-methylpyrrolidine, 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / CH2Cl2 / 20 h / 20 °C
6: 85 percent / NH3 / methanol / 16 h / 0 - 5 °C
7: 54 percent / TFA / CH2Cl2 / 0.17 h
View Scheme
参考文献
Roelen, H. C. P. F.; Brugghe, H. F.; Elst, H. van den; Klein, J. C.; Marel, G. A. van der; Boom, J. H. van
Recueil des Travaux Chimiques des Pays-Bas, 1992 , vol. 111, p. 227 - 234
1: 88 percent / pyridine / 1 h / 20 °C
2: conc. NH4OH / dioxane / 24 h / 50 °C
3: N-methylimidazole (NMI) / pyridine / 0.5 h / 20 °C
4: 81 percent / 4-(dimethylamino)pyridine (DMAP), triethylamine / CH2Cl2 / 16 h
5: 66 percent / N-methylpyrrolidine, 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / CH2Cl2 / 20 h / 20 °C
6: 88 percent / NH3 / methanol / 16 h / 0 - 5 °C
7: 49 percent / TFA / CH2Cl2 / 0.17 h
View Scheme
参考文献
Roelen, H. C. P. F.; Brugghe, H. F.; Elst, H. van den; Klein, J. C.; Marel, G. A. van der; Boom, J. H. van
Recueil des Travaux Chimiques des Pays-Bas, 1992 , vol. 111, p. 227 - 234
