2-羟基-6-甲氧基喹噁啉合成路线 （共 7 条）
反应条件
trichlorophosphate 1 h; Heating / reflux;
参考文献
MERCK and CO., INC.
Patent: WO2007/27532 A2, 2007 ;
Location in patent: Page/Page column 35 ;
WO 2007/027532 A2
反应条件
in ethyl acetate; trichlorophosphate
参考文献
Bristol-Myers Squibb Company; Rajamani, Ramkumar; Renduchintala, Kishore V.; Sarkunam, Kandhasamy; Nagalakshmi, Pulicharla; Meanwell, Nicholas A.; Scola, Paul Michael
Patent: US2013/142754 A1, 2013 ;
Location in patent: Page/Page column ;
反应条件
trichlorophosphate
1 h; Heating / reflux;
参考文献
MERCK and CO., INC.
Patent: WO2007/27532 A2, 2007 ;
Location in patent: Page/Page column 35 ;
WO 2007/027532 A2
反应条件
in ethyl acetate; trichlorophosphate
参考文献
Bristol-Myers Squibb Company; Rajamani, Ramkumar; Renduchintala, Kishore V.; Sarkunam, Kandhasamy; Nagalakshmi, Pulicharla; Meanwell, Nicholas A.; Scola, Paul Michael
Patent: US2013/142754 A1, 2013 ;
Location in patent: Page/Page column ;
反应条件
1: With trichlorophosphate
1 h; Reflux;
2: With water
3: With sodium carbonate
参考文献
Bristol-Myers Squibb Company
Patent: US2009/270405 A1, 2009 ;
Location in patent: Page/Page column 89 ;
反应条件
trichlorophosphate
1 h; Heating / reflux;
参考文献
MERCK and CO., INC.
Patent: WO2007/27532 A2, 2007 ;
Location in patent: Page/Page column 35 ;
WO 2007/027532 A2
反应条件
trichlorophosphate in tetrahydrofuran
T=65°C;
参考文献
Ramurthy, Savithri; Costales, Abran; Jansen, Johanna M.; Levine, Barry; Renhowe, Paul A.; Shafer, Cynthia M.; Subramanian, Sharadha
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1678 - 1681
