5-溴-2-吗啉-4-苯胺合成路线 (共 2 条)
反应条件
potassium dihydrogenphosphate; zinc in tetrahydrofuran T=80°C; 24 h;
参考文献
Garino, Cedrik; Tomita, Taisuke; Pietrancosta, Nicolas; Laras, Younes; Rosas, Roselyne; Herbette, Gaetan; Maigret, Bernard; Quelever, Gilles; Iwatsubo, Takeshi; Kraus, Jean-Louis
Journal of Medicinal Chemistry, 2006 , vol. 49, # 14 p. 4275 - 4285
反应条件
1: 73 percent / triethylamine / propan-2-ol / 24 h / 70 °C 2: 63 percent / Zn; aq. KH2PO4 / tetrahydrofuran / 24 h / 80 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 14 p. 4275 - 4285