1,2,3,4-四氢异喹啉合成路线 （共 340 条）
反应条件
in N,N-dimethyl-formamide
T=0 - 5°C; 5 h;
参考文献
Ganguly, Swastika; Murugesan
Journal of the Indian Chemical Society, 2010 , vol. 87, # 7 p. 879 - 885
参考文献
Gray et al.
Journal of the American Chemical Society, 1955 , vol. 77, p. 3536,3540
参考文献
Thesing; Mayer
Justus Liebigs Annalen der Chemie, 1957 , vol. 609, p. 46,56
反应条件
in ethanol
1 h; Heating;
参考文献
Elslager; Colbry; Davoll; Hutt; Johnson; Werbel
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1740 - 1743
反应条件
1: xylene / 24 h / 120 - 130 °C
2: hydrazine hydrate / ethanol / 1 h / Heating
View Scheme
参考文献
Contreras, Jean-Marie; Rival, Yveline M.; Chayer, Said; Bourguignon, Jean-Jacques; Wermuth, Camille G.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 730 - 741
参考文献
Okimoto, Mitsuhiro; Yoshida, Takashi; Hoshi, Masayuki; Hattori, Kazuyuki; Komata, Masashi; Numata, Kaori; Tomozawa, Kenta
Australian Journal of Chemistry, 2007 , vol. 60, # 4 p. 236 - 242
反应条件
1: aq. NaOCl / CH2Cl2
2: NaOH / methanol; CH2Cl2
3: 72 percent / KNO3 / H2SO4 / 6 h / 20 - 60 °C
View Scheme
参考文献
Bohe, Luis; Kammoun, Majed
Tetrahedron Letters, 2004 , vol. 45, # 4 p. 747 - 751
反应条件
1: sodium hydroxide; N-bromosuccinmide / dichloromethane / |Inert atmosphere
2: potassium nitrate / sulfuric acid / 2 h / 20 - 40 °C / |Inert atmosphere
View Scheme
参考文献
Chen, Ying; Crockett, Richard D.; Wang, Xin; Larsen, Robert D.; Cui, Sheng; Faul, Margaret M.
Synlett, 2013 , vol. 24, # 3 art. no. ST-2012-Y0825-C, p. 301 - 304
反应条件
1: MBS; NaOH / CH2Cl2
2: 76 percent / KNO3; H2SO4
3: 88 percent / tin(II) chloride dihydrate; conc. HCl / ethanol / 1 h / 60 °C
View Scheme
参考文献
Heer, Jag P.; Harling, John D.; Thompson, Mervyn
Synthetic Communications, 2002 , vol. 32, # 16 p. 2555 - 2563
参考文献
Wegler; Frank
Chemische Berichte, 1937 , vol. 70, p. 1279,1285
