1,2,3,4-四氢异喹啉合成路线 （共 340 条）
反应条件
sodium hydroxide in ethanol 4 h; Ambient temperature;
参考文献
Shinohara, Tatsumi; Toda, Jun; Sano, Takehiro
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 5 p. 813 - 819
参考文献
Alanine, Alexander; Flohr, Alexander; Miller, Aubry Kern; Norcross, Roger David; Riemer, Claus
Patent: US2002/45615 A1, 2002 ;
反应条件
ammonium formate; palladium on activated charcoal in methanol 0.5 h; Heating;
参考文献
Synthetic Communications, , vol. 20, # 18 p. 2815 - 2819
反应条件
in dichloromethane; sulfuric acid
反应条件
NH4Br; ethylenediamine T=60°C; 5 h; Microwave irradiationInert atmosphereneat (no solvent);
参考文献
Shimizu, Yuhei; Morimoto, Hiroyuki; Zhang, Ming; Ohshima, Takashi
Angewandte Chemie - International Edition, 2012 , vol. 51, # 34 p. 8564 - 8567
反应条件
NH4Br; ethylenediamine T=70°C; 5 h; Microwave irradiationInert atmosphereneat (no solvent);
参考文献
Shimizu, Yuhei; Morimoto, Hiroyuki; Zhang, Ming; Ohshima, Takashi
Angewandte Chemie - International Edition, 2012 , vol. 51, # 34 p. 8564 - 8567
反应条件
NH4Br; ethylenediamine T=90°C; 5 h; Microwave irradiationInert atmosphereneat (no solvent);
参考文献
Shimizu, Yuhei; Morimoto, Hiroyuki; Zhang, Ming; Ohshima, Takashi
Angewandte Chemie - International Edition, 2012 , vol. 51, # 34 p. 8564 - 8567
反应条件
potassium hydroxide; water; pentacarbonyliron(0) in methanol T=300°C; P=20685.9 - 51714.8 Torr; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 49, # 7 p. 1266 - 1270
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Beaumont, David; Waigh, Roger D.; Sunbhanich, Methi; Nott, Michael W.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 507 - 515
