1,2-二(溴甲基)苯合成路线 （共 196 条）
反应条件
Amberlyst A 26; carbonate form in benzene 2 h; Heating;
参考文献
Cardillo, Giuliana; Orena, Mario; Porzi, Gianni; Sandri, Sergio
Synthesis, 1981 , # 10 p. 793 - 794
反应条件
silver tetrafluoroborate; water in 1,4-dioxane T=80°C; 10 h; Yield given. Yields of byproduct given;
参考文献
Kirmse, Wolfgang; Kund, Klaus
Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2325 - 2332
反应条件
bis-{4-methoxy-phenyl}-selenoxyde; sodium hydrogencarbonate in acetonitrile T=75°C; 5 h;
参考文献
Chemistry Letters, , p. 891 - 892
反应条件
1: 54 percent / Zn / acetonitrile / 4 h / 50 °C 2: 97 percent / KF / ethanol / Ambient temperature 3: 65 percent / m-chloroperbenzoic acid / dimethylformamide / 14 h / 50 °C View Scheme
参考文献
Tamao, Kohei; Yoshida, Jun-ichi; Akita, Munetaka; Sugihara, Yoshihiro; Iwahara, Takahisa; Kumada, Makoto
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 1 p. 255 - 260
反应条件
sulfuric acid; potassium nitrate T=0°C; 4 h;
参考文献
Hay, Michael P.; Hicks, Kevin O.; Pchalek, Karin; Lee, Ho H.; Blaser, Adrian; Pruijn, Frederik B.; Anderson, Robert F.; Shinde, Sujata S.; Wilson, William R.; Denny, William A.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 21 p. 6853 - 6865
反应条件
sodium azide in N,N-dimethyl-formamide T=60°C; 5 h; Inert atmosphere;
参考文献
Gigant, Nicolas; Claveau, Elise; Bouyssou, Pascal; Gillaizeau, Isabelle
Organic Letters, 2012 , vol. 14, # 3 p. 844 - 847
反应条件
1: 75 percent / NaOMe / 4 h / Heating 2: 6 N aq. HCl / 4 h / Heating 3: 76 percent / p-TsOH*H2O / toluene / 30 h / Heating 4: 90 percent / NaOH / methanol / 6 h / Ambient temperature View Scheme
参考文献
Kammermeier; Lerch; Sommer
Synthesis, 1992 , # 11 p. 1157 - 1160
反应条件
water; N-ethyl-N,N-diisopropylamine; triphenylphosphine; Na2[PdCl4] in various solvent(s) T=70°C; P=760 Torr;
参考文献
Jones, Ray V.H.; Lindsell, W. Edward; Paddon-Jones, Greg C.; Palmer, Daniel D.; Preston, Peter N.; Rosair, Georgina M.; Whitton, Alan J.
Journal of Organometallic Chemistry, 2006 , vol. 691, # 11 p. 2378 - 2385
反应条件
NaCo(CO)4 in tetrahydrofuran 8 h; Heating;
参考文献
Devasagayaraj, A.; Rao. S. Achyutha; Periasamy, M.
Journal of Organometallic Chemistry, 1991 , vol. 403, # 3 p. 387 - 391
反应条件
1: 90 percent / K2CO3 / butan-2-one / 24 h / Heating 2: 92 percent / KOH / aq. ethanol / 12 h / Heating 3: oxalyl chloride, pyridine / benzene / 5 h / Heating 4: NaN3 / acetonitrile 5: cyclohexane / 2 h / Heating 6: 50percent acetic acid / tetrahydrofuran / 8 h View Scheme
参考文献
Mueller, Paul; Miao, Zhongshan
Helvetica Chimica Acta, 1994 , vol. 77, p. 2051 - 2059
