4-溴-2-硝基萘-1-胺合成路线 （共 21 条）
反应条件
1: (i) NaNO2, (ii) (deamination) 2: (reduction) 3: (i) NaNO2, (ii) aq. H2SO4 4: OH- 5: dimethylformamide View Scheme
参考文献
Tsuno,Y. et al.
Bulletin of the Chemical Society of Japan, 1975 , vol. 48, p. 3347 - 3355
反应条件
1: (i) NaNO2, (ii) (deamination) 2: (reduction) 3: (i) NaNO2, (ii) aq. H2SO4 4: OH- 5: dimethylformamide 6: aq. H2SO4 / acetic acid View Scheme
参考文献
Tsuno,Y. et al.
Bulletin of the Chemical Society of Japan, 1975 , vol. 48, p. 3347 - 3355
反应条件
sulfuric acid in ethanol
T=20°C; 4 h;
参考文献
Oh, Soo-Jin; Hwang, Seok Jin; Jung, Jonghoon; Yu, Kuai; Kim, Jeongyeon; Choi, Jung Yoon; Hartzell, H. Criss; Roh, Eun Joo; Justin Lee
Molecular Pharmacology, 2013 , vol. 84, # 5 p. 726 - 735
反应条件
1: glacial acetic acid; nitric acid / 60 - 70 °C
2: potash; alcohol
View Scheme
参考文献
Liebermann
Justus Liebigs Annalen der Chemie, 1876 , vol. 183, p. 250
反应条件
1: pyridine
2: glacial acetic acid; nitric acid
3: alcoholic ammonia / 180 °C
View Scheme
参考文献
Morgan; Godden
Journal of the Chemical Society, 1910 , vol. 97, p. 1716
参考文献
Morgan; Godden
Journal of the Chemical Society, 1910 , vol. 97, p. 1716
反应条件
bromine; acetic acid
参考文献
Hodgson; Elliott
Journal of the Chemical Society, 1935 , p. 1850,1852
Full Text Show Details
Consden; Kenyon
Journal of the Chemical Society, 1935 , p. 1596
反应条件
1: glacial acetic acid; bromine
2: concentrated sulfuric acid / und Versetzen mit Wasser
View Scheme
参考文献
Meldola; Desch
Journal of the Chemical Society, 1892 , vol. 61, p. 769
反应条件
1: glacial acetic acid / Beim Bromieren
2: glacial acetic acid; nitric acid
3: alcoholic ammonia / 180 °C
View Scheme
参考文献
Morgan; Godden
Journal of the Chemical Society, 1910 , vol. 97, p. 1716
反应条件
1: glacial acetic acid; nitric acid
2: alcoholic ammonia / 180 °C
View Scheme
参考文献
Morgan; Godden
Journal of the Chemical Society, 1910 , vol. 97, p. 1716
