5-溴-1-甲基-1H-吲哚-2-羧酸合成路线 （共 2 条）
反应条件
1: With methanol; lithium hydroxide; water
T=85°C; 0.583333 h;
2: With hydrogenchloride; water in methanol
参考文献
Hulme, Christopher; Ncube, Mghele Vellah; Norman, Mark H.; Ognyanov, Vassil I.; Pettus, Liping H.; Wang, Xianghong; Zhu, Jiawang
Patent: US2005/165049 A1, 2005 ;
Location in patent: Page/Page column 14 ;
US 20050165049 A1
反应条件
1: With sodium hydroxide in 1,4-dioxane; water
T=80°C; 2 h; Inert atmosphere;
2: With hydrogenchloride in 1,4-dioxane; water
T=23°C; pH=3;
参考文献
Sokolovs, Igors; Lubriks, Dmitrijs; Suna, Edgars
Journal of the American Chemical Society, 2014 , vol. 136, # 19 p. 6920 - 6928
