反应条件
1: 1) t-BuOK / 1) THF, 0 deg C, 30 min, 2) THF, 0 deg C, 4 h
2: H2, NaHCO3 / 10percent Pd/C / methanol / 760 Torr
3: 14.2 g / KOH / ethanol / Heating
4: 83 percent Turnov. / pyridine / CH2Cl2 / 1.) 0 deg C, 2 h, 2.) r.t., 3 h
5: DOWEX-50X8-400R, MeOH / 20 h / 50 °C
6: Et3N / CH2Cl2 / 1 h / 0 °C
7: 10.6 g / LiI / dimethylformamide / 3.5 h / 90 °C
8: 72 percent Turnov. / AgNO2 / diethyl ether / 1.) 0 deg C, 1 d, 2.) r.t., 12 d, in darkness
View Scheme
参考文献
Ko, Soo Sung; Confalone, Pat N.
Tetrahedron, 1985 , vol. 41, # 17 p. 3511 - 3518
