6,7-二氢-5H-环戊并[b]吡啶-7-基 乙酸酯合成路线 （共 13 条）
反应条件
potassium hydroxide in ethanol T=20°C; 1 h;
参考文献
Pereira, Cidaliasilva; Salgado, Sofia; Rizzo-Aguiar, Fabio; Garcia-Mera, Xerardo; Rodriguez-Borges, Josee.
Synlett, 2013 , vol. 24, # 7 art. no. ST-2012-D1091-L, p. 837 - 838
反应条件
sulfuric acid T=125°C; 2 h; Title compound not separated from byproducts;
参考文献
SANOFI
Patent: EP2368876 A1, 2011 ;
Location in patent: Page/Page column 25 ;
反应条件
sulfuric acid T=20 - 125°C; 2 h;
参考文献
EURO-CELTIQUE S.A.
Patent: WO2007/28638 A1, 2007 ;
Location in patent: Page/Page column 73-74 ;
WO 2007/028638 A1
反应条件
sulfuric acid T=125°C; 2 h; Title compound not separated from byproducts;
参考文献
SANOFI
Patent: EP2368876 A1, 2011 ;
Location in patent: Page/Page column 25 ;
反应条件
sulfuric acid T=130°C;
参考文献
Robison
Journal of the American Chemical Society, 1958 , vol. 80, p. 6254,6255
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Giam, C. S.; Ambrozich, Deborah
Journal of the Chemical Society, Chemical Communications, 1984 , # 5 p. 265 - 266
反应条件
1: potassium hydroxide / ethanol / 1 h / 20 °C 2: triethylamine; oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 24 h / -78 °C / |Inert atmosphere View Scheme
参考文献
Pereira, Cidaliasilva; Salgado, Sofia; Rizzo-Aguiar, Fabio; Garcia-Mera, Xerardo; Rodriguez-Borges, Josee.
Synlett, 2013 , vol. 24, # 7 art. no. ST-2012-D1091-L, p. 837 - 838
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Giam, C. S.; Ambrozich, Deborah
Journal of the Chemical Society, Chemical Communications, 1984 , # 5 p. 265 - 266
反应条件
water
T=20 - 100°C; 4 h;
参考文献
SANOFI
Patent: EP2368876 A1, 2011 ;
Location in patent: Page/Page column 25 ;
反应条件
1: 94 percent / 30percent H2O2 / acetic acid / 12 h / 75 °C
2: 77 percent / 3.5 h / 100 °C
View Scheme
参考文献
Giam, C. S.; Ambrozich, Deborah
Journal of the Chemical Society, Chemical Communications, 1984 , # 5 p. 265 - 266
