(2-氨基-3-氟苯基)甲醇合成路线 (共 2 条)
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether
T=0 - 20°C;
2: With water; sodium hydroxide in tetrahydrofuran; diethyl ether
参考文献
AMGEN INC.
Patent: US2010/331306 A1, 2010 ;
Location in patent: Page/Page column 19 ;
反应条件
manganese(IV) oxide in dichloromethane
T=20°C;
参考文献
Ida, Yoshihiro; Matsubara, Ayaka; Nemoto, Toru; Saito, Manabu; Hirayama, Shigeto; Fujii, Hideaki; Nagase, Hiroshi
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 19 p. 5810 - 5831