2-甲基-8-羟基-4-喹唑啉酮合成路线 (共 7 条)
反应条件
boron tribromide in dichloromethane demethylation; 24 h; Heating;
参考文献
Newcastle University Ventures Limited
Patent: US6156739 A1, 2000 ;
反应条件
1: 31 percent / pyridine / tetrahydrofuran / 25 °C 2: 67 percent / aq. NaOH / Ambient temperature 3: 65 percent / BBr3 / CH2Cl2 / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 26 p. 5247 - 5256
反应条件
1: 67 percent / aq. NaOH / Ambient temperature 2: 65 percent / BBr3 / CH2Cl2 / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 26 p. 5247 - 5256
反应条件
N,N-diethylaniline Heating; Yield given;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 1182 - 1184
反应条件
1: water; NH3 2: aqueous HBr View Scheme
参考文献
Journal of Scientific and Industrial Research, , vol. 17 C, p. 193,194
参考文献
WO2004/31161 A1, ;
Page 117 ;
反应条件
trichlorophosphate 0.5 h; Heating / reflux;
参考文献
Prana Biotechnology Limited
Patent: WO2004/31161 A1, 2004 ;
Location in patent: Page 38; 43 ;