5-氰基-3-吡啶甲酸乙酯合成路线 （共 9 条）
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride
T=100°C; P=5171.5 Torr;
参考文献
Head, Robert A.; Ibbotson, Arthur
Tetrahedron Letters, 1984 , vol. 25, # 51 p. 5939 - 5942
反应条件
1: in ethanol
T=70°C; 2 h;
2: With ammonium acetate in ethanol
T=90°C; 4 h;
3: With sodium hydroxide in ethanol; water
T=20°C; Product distribution / selectivity;
参考文献
Sankio Chemical Co., Ltd.
Patent: EP1559711 A1, 2005 ;
Location in patent: Page/Page column 24-25 ;
反应条件
1: in ethanol
T=70°C; 2 h;
2: With ammonium acetate in ethanol
T=90°C; 4 h;
3: With sodium hydroxide in ethanol; water
T=20°C; Product distribution / selectivity;
参考文献
Sankio Chemical Co., Ltd.
Patent: EP1559711 A1, 2005 ;
Location in patent: Page/Page column 25 ;
反应条件
pyridine; trichlorophosphate
参考文献
Bohlmann et al.
Justus Liebigs Annalen der Chemie, 1954 , vol. 587, p. 162,167
Chemische Berichte, 1956 , vol. 89, p. 792,796
参考文献
Wallenfels; Schuely
Justus Liebigs Annalen der Chemie, 1959 , vol. 621, p. 106,119
反应条件
1: SOCl2
2: benzene; aqueous NH3
3: POCl3; pyridine
View Scheme
参考文献
Bohlmann et al.
Justus Liebigs Annalen der Chemie, 1954 , vol. 587, p. 162,167
Chemische Berichte, 1956 , vol. 89, p. 792,796
反应条件
1: benzene; aqueous NH3
2: POCl3; pyridine
View Scheme
参考文献
Bohlmann et al.
Justus Liebigs Annalen der Chemie, 1954 , vol. 587, p. 162,167
Chemische Berichte, 1956 , vol. 89, p. 792,796
反应条件
1: ethanolic KOH
2: SOCl2
3: benzene; aqueous NH3
4: POCl3; pyridine
View Scheme
参考文献
Bohlmann et al.
Justus Liebigs Annalen der Chemie, 1954 , vol. 587, p. 162,167
Chemische Berichte, 1956 , vol. 89, p. 792,796
反应条件
2: 200 °C
View Scheme
参考文献
Wallenfels; Schuely
Justus Liebigs Annalen der Chemie, 1959 , vol. 621, p. 106,119
