5-溴-2-甲氧基-4-甲基苯甲酸合成路线 （共 9 条）
反应条件
1: With sodium hydroxide in ethanol; water
0.5 h; Heating / reflux;
2: With hydrogenchloride in water
pH=2;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO KG
Patent: WO2004/108673 A2, 2004 ;
Location in patent: Page 47-49 ;
反应条件
sodium hydroxide; copper
参考文献
Marzin
Journal fuer Praktische Chemie (Leipzig), 1933 , vol. <2> 138, p. 103,106
反应条件
bromine
Irradiation;
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
反应条件
1: iodine; bromine / 10 - 15 °C
2: aqueous nitric acid
3: aqueous methanol. NaOH-solution; copper-powder
View Scheme
参考文献
Marzin
Journal fuer Praktische Chemie (Leipzig), 1933 , vol. <2> 138, p. 103,106
反应条件
1: aqueous nitric acid
2: aqueous methanol. NaOH-solution; copper-powder
View Scheme
参考文献
Marzin
Journal fuer Praktische Chemie (Leipzig), 1933 , vol. <2> 138, p. 103,106
反应条件
1: aq. NaOH
2: aq. NaOCl
3: Br2 / Irradiation
View Scheme
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
反应条件
1: AlCl3 / 165 °C
2: aq. NaOH
3: aq. NaOCl
4: Br2 / Irradiation
View Scheme
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
反应条件
1: aq. NaOCl
2: Br2 / Irradiation
View Scheme
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
参考文献
Marzin
Journal fuer Praktische Chemie (Leipzig), 1933 , vol. <2> 138, p. 103,106
