(R)-4-苯基-2-恶唑烷酮合成路线 （共 68 条）
反应条件
air; oxygen; potassium iodide; PdI2 in methanol T=100°C; Cyclization; oxidative carbonylation; P=45603.1 Torr; 15 h;
参考文献
Gabriele, Bartolo; Salerno, Giuseppe; Brindisi, Donatella; Costa, Mirco; Paolo Chiusoli, Gian
Organic Letters, 2000 , vol. 2, # 5 p. 625 - 626
反应条件
1: With lithium hydroxide hydrate; dihydrogen peroxide in tetrahydrofuran; water T=20°C; 12 h; Inert atmosphere; 2: With hydrogenchloride in water pH=3; Inert atmosphere;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 4 p. 439 - 463
反应条件
N(Et)4(1+)*(2-pyrrolidone-anion); p-toluenesulfonyl chloride in acetonitrile T=20°C; Carboxylation; cyclization; Product distribution; Further Variations:SolventsReagents;
参考文献
Paz, Jairo; Perez-Balado, Carlos; Iglesias, Beatriz; Munoz, Luis
Journal of Organic Chemistry, 2010 , vol. 75, # 9 p. 3037 - 3046
反应条件
1: With lithium hydroxide hydrate; dihydrogen peroxide in tetrahydrofuran; water T=20°C; 12 h; Inert atmosphere; 2: With hydrogenchloride in water pH=3; Inert atmosphere;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 4 p. 439 - 463
反应条件
1: With lithium hydroxide hydrate; dihydrogen peroxide in tetrahydrofuran; water T=20°C; 12 h; Inert atmosphere; 2: With hydrogenchloride in water pH=3; Inert atmosphere;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 4 p. 439 - 463
反应条件
dihydrogen peroxide; lithium hydroxide hydrate in tetrahydrofuran; water T=20°C; 4 h; Cooling with ice;
参考文献
EP2671878 A1, ;
Paragraph 0070; 0071 ;
反应条件
thionyl chloride in tetrahydrofuran T=0°C; 3 h;
参考文献
Matsunaga, Hirofumi; Ishizuka, Tadao; Kunieda, Takehisa
Tetrahedron, 1997 , vol. 53, # 4 p. 1275 - 1294
反应条件
N(Et)4ClO4; triethylamine in acetonitrile T=-20°C; P=760 Torr; ElectrolysisMg anode; Pb cathode;
参考文献
Organic Letters, , vol. 4, # 16 p. 2617 - 2620
反应条件
potassium carbonate; Rh2(S-TCPTAD)4 in dichloromethane T=23°C; 4 h; Product distribution / selectivity;
参考文献
The Research Foundation of State University of New York
Patent: US7385064 B1, 2008 ;
Location in patent: Page/Page column 60; 65 ;
反应条件
potassium carbonate T=120°C;
参考文献
Ito; Sasaki; Tamoto; Sunagawa; Terashima
Tetrahedron, 1991 , vol. 47, # 16-17 p. 2801 - 2820
