(S)-1-甲基-3-氨基哌啶合成路线 (共 2 条)
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 1 h;
参考文献
ASTEX THERAPEUTICS LIMITED
Patent: WO2006/77414 A1, 2006 ;
Location in patent: Page/Page column 140 ;
WO 2006/077414 A1
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran
T=0 - 20°C;
2: With water; Sodium potassium tartrate
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/106326 A1, 2006 ;
Location in patent: Page/Page column 97 ;
WO 2006/106326 A1