in ethanol; water T=20°C; 6.16667 h;

1: piperazine; piperazine Dihydrochloride in water 0.0833333 h; 2: 1-(p-fluorophenylcarbonyl)imidazole With sodium chloride in water 0.5 h; 3: With sodium hydroxide in water chemoselective reaction;

1: hydroxylamine / acetonitrile; water / 14 h / 23 °C 2: 4-nitrophenylsulfonyl chloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 0 °C / |Inert atmosphere View Scheme

imidazole hydrochloride in water T=20°C; 0.166667 h;